There are currently 25 local United Ways serving the communities of South Carolina.
- United Way of Aiken County, Inc.
- United Way of Anderson County
- Barnwell County United Way
- Black River United Way
- United Way of Chester County
- United Way of Chesterfield County
- United Way of Darlington
- Dillon County United Way
- United Way of Edgefield County
- United Way of Florence County
- United Way of Greenville County
- United Way of Greenwood and Abbeville Counties
- United Way of Hartsville
- United Way of Horry County
- United Way of Kershaw County
- United Way of Lancaster County
- United Way of Laurens County
- United Way of the Lowcountry, Inc.
- United Way of the Midlands
- United Way of Oconee County
- United Way of Pickens County
- United Way of the Piedmont
- United Way of Sumter, Clarendon and Lee Counties
- Trident United Way
- United Way of York County